Yes, Vitamin A deficiency can lead to a condition called keratosis pilaris, which causes rough, dry skin bumps, often on the arms, thighs, or cheeks. This occurs because Vitamin A is essential for maintaining healthy skin and supporting normal cell turnover. A deficiency can lead to a buildup of keratin, clogging hair follicles and causing these bumps. Increasing Vitamin A intake through diet or supplements may help improve the condition over time.