Vitamin B1 deficiency, also known as beriberi, can present with a range of symptoms depending on its severity. Common signs include:
- Fatigue and low energy
- Irritability and mood changes
- Muscle weakness
- Nerve damage, causing tingling or numbness in the hands and feet
- Difficulty walking or maintaining balance
- Swelling in the lower extremities (wet beriberi)
- Memory loss and confusion (in severe cases, such as Wernicke-Korsakoff syndrome)
Research from The Lancet Neurology (2021) highlights the prevalence of thiamine deficiency in populations with high carbohydrate intake but limited dietary diversity (The Lancet Neurology).
Another study published in Nutrients (2020) connects low thiamine levels with chronic conditions such as diabetes and heart disease, emphasizing the importance of early detection and intervention (Nutrients, MDPI).